Native to southern Europe, lemon balm (Melissa officinalis) is a hardy herb of the Lamiaceae family, which has been used for centuries to improve cognition and mood, and reduce anxiety and stress. Indeed, melissa leaves can help to moderate the subjective sensation of stress, without altering cognitive performance. Melissa is mainly composed of rosmarinic acid which has the ability to inhibit the enzyme GABAtransaminase. This inhibition results in an accumulation of gaba in the brain which is an inhibitor of the central nervous system. Melissa has relaxing properties, at least equal to synthetic products, unlike other natural products. Although it is frequently found in the wild, it has been cultivated for centuries, particularly in Anjou (France). Thus, melissa is an effective natural solution for calming animals and therefore contributing to their well-being.