Resistant capacity of the encapsulated grape extract during ruminal fermentation: an Ex-vitro study

nor grape bp

Last August 2022, in Thessaloniki (Greece) Doctor Bui (DVM, Nor-Feed R&D team) shared new data obtained with our encapsulated grape extract during the 70th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural product research (GA).

Rumen-by-pass formula of Nor-Grape® to protect active molecules from

Ruminal retention

Natural grape extract constituted of polyphenols has been proven for their beneficial effects on antioxidant defense and hormonal improvement in ruminants [1]. It is proven that a rumen-by-pass formula of grape extract is crucial to protect its’ active molecules from degradation and deformation during ruminal retention period [3,4]. This present study measures the resistant capacity of the encapsulated grape polyphenols, anthocyanins and antioxidant activity (PNGE, Nor-Grape® BP-O) under ruminal fermentation condition (ex-vitro model), in comparison with its’ unprotected version, a soluble dry grape extract (UNGE).

At the beginning of the experiment (T0), both extracts possessed an equivalent level of polyphenols, anthocyanins and antioxidant activity. After 6 hours of fermentation (T6), UNGE content in polyphenol and anthocyanins reduced dramatically whereas PNGE content slightly reduced (2,5 to 3 times less reduction comparing to UNGE). Last but not least, the antioxidant capacity strongly reduced after 6 hours fermentation for UNGE (below 35%), whereas the antioxidant activity for PNGE remain above 80%. (Data not presented).

Thus, the obtained results demonstrated the high sensitivity of grape extract when undergoing rumen fermentation during 6 hours. In contrast, during this study the encapsulated version (PNGE) permits to reduce the loss of polyphenols, anthocyanins and antioxidant activity during rumen fermentation.

Full data (PI 90 and Poster) and references available upon request

ngbpo species

Our natural rumen-protected grape extract to compensate oxidative stress

Nor-Grape® BP-O

Nor-Grape® BP-O is a premix of additives composed of encapsulated natural grape extracts, whose polyphenol content and antioxidant activity are protected against rumen fermentation.


Products from the range


Nor-Grape® 80

Compensate oxidative stress

Nor-Grape® BP-O

Compensates oxidative stress